ceesdekker No Further a Mystery

ceesdekker No Further a Mystery

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Nanotechnology offers a range of options to lead to biology. Below I'll existing illustrations wherever nanofabrication – a chance to make confined buildings with dimensions at will – is employed to examine the biophysics of single molecules and cells. I will present some examples from our lab:

But how can morality, the dignity from the human being, my experience of your which means of lifestyle, abide by with the movement of atoms? A purely naturalistic standpoint fails below; a Christian viewpoint, I do think, is a way more affordable way to interpret these areas of actuality.’

[Laughs] ‘It was absolutely a terrific chance! At time, I was well aware that it could go Completely wrong Which I could develop into a lot less productive, but I just ignored that. Curiosity has always been my strongest driving drive. And fortunately all of it worked out.’

2007, initial authentic-time detection of strand exchange in homologous recombination by RecA; discovery of a very low persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial cell division; and first at any time analyze on the dynamics DNA supercoils and the invention of supercoil hopping

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes

‘In the beginning we checked out Organic methods that has a Actual physical see and acted on The idea of your resources we understood. It took a several years right before we began Doing work extra on the big biological concerns. I then began to simply call it nanobiology, a time period that did not exist at the time.

2011, initially in vitro measurements of transport across just one biomimetic nuclear pore complicated; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination

Let's say, rather than applying typical top-down silicon electronics, transistors may very well be developed from The underside up making use of one natural molecules given that the switching factors? This concept, which became The premise of these days’s subject of molecular electronics, initial emerged from the cees dekker 1970s.

Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making course of action

‘The concept There's this type of matter to be a beginning, a large bang, is previously a fascinating signpost to look at that there was a creator. But much more typically, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is usually a naturalistic worldview: fundamentally, you will find only atoms and organic forces that we will evaluate.

Afterwards we spoke yet again briefly due to the fact Dekker felt that our dialogue of his faith promptly became purely philosophical, While it also concretely will help him in his work.

Visualization of unstained DNA nanostructures with advanced in-concentrate transmission electron microscopy procedures

Strong-state nanopores have verified to get a amazingly flexible probe for single-molecule analysis of DNA. I will explain many of our the latest conclusions – specially DNA knots – together with our initiatives to develop the abilities of sound-condition nanopores even additional, within the path of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.