5 Simple Techniques For https://www.ceesdekker.net
5 Simple Techniques For https://www.ceesdekker.net
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Nanotechnology presents An array of possibilities to contribute to biology. Listed here I will current examples wherever nanofabrication – a chance to make confined buildings with Proportions at will – is used to examine the biophysics of single molecules and cells. I'll existing some illustrations from our lab:
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Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I
Our function was swiftly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors created from solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first at any time examine of the dynamics DNA supercoils and the invention of supercoil hopping
Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: rapid electron relay to redox enzymes and zeptomole protein-movie voltammetry
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has focused on researching cell division with germs on chip, while his best curiosity is in the way of acknowledging synthetic cells.
2000, discovery that nanotubes can carry amazing large existing densities; fixed the controversial issue of electronic transportation as a result of DNA molecules by measurements of insulating conduct at The only molecule stage; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
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Right now, we also recognized that it should be possible to use a single semiconducting carbon nanotube to make a transistor — and we established out to really make it. We stretched specific semiconducting nanotubes across metallic electrodes and utilized the underlying silicon substrate to be a gate electrode, developing The fundamental three-terminal structure of the discipline-result transistor (Fig.
Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim on the pore is highlighted in crimson, along with a 3D rendering of the movement on the DNA rod is displayed.
Later on we spoke once more briefly due to the fact Dekker felt that our dialogue of his religion immediately became purely philosophical, whereas In addition, it concretely can help him in his do the job.
Visualization of unstained DNA nanostructures with Superior in-emphasis transmission electron microscopy approaches
Finally, I will briefly sketch some of our Suggestions to investigate the constructing ceesdekker of synthetic cells, exclusively our 1st techniques to determine artificial mobile division.